Use the “Secondary(二级参数)” statement to define the AUC, such as secondary (AUC=A1Dose/Cl), and then view the value of this parameter in the “Secondary” worksheet under the “Results(结果)” subtab. Implementation 1: “Methods for defining secondary parameters” It can be subdivided into two categories when calculating the AUC based on the formula. The AUC calculated based on the formula is equivalent to AUCinf because it is an analytical solution. Key words: Phoenix WinNonlin, Phoenix NLME, PML, Phoenix Modeling Language, AUC, AUClast, AUCinf, pAUC, Secondary parameter, Pharmacokinetic, PK/PD, Pharmacometrics Formula-based AUC calculation There are two main methods for calculating the AUC in PML, formulas-based and based on integrals-based. Microsampling options available with corresponding high-sensitivity analytical capabilities Immunological methods and analysis. One of the operations that is often required to create a model using the Phoenix Modeling Language (PML) is to calculate the AUC. Calculation of TK parameters using WinNonlin (v 8.1) Specific parameters such as C max, T max, AUC, t 1/2, clearance (CL), volume of distribution (VD), etc. Some calculation methods for AUC in PML Yongchao Fu / Some calculation methods for AUC in PML - Yongchao Fu | 付永超
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |